Emergence of system roles in normative neurodevelopment

Abstract. The human brain is a complex system displaying intricate, dynamic functions. In a multidisciplinary effort, the recent application of tools from network science to characterize the interconnected nature of the brain has enabled a tremendous advance in our understanding of cognition. Here, we develop and apply an extension of these tools to define and characterize the role of cognitive systems in the larger scale brain network, and to map how these roles change during adolescent development, providing an important context for understanding psychopathology. Our results are also consistent with the hypothesis that individual variation in network configuration implies differential vulnerability to cognitive abilities or deficits.

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